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Anemonia sulcata
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Anemonia sulcata, or Mediterranean snakelocks sea anemone, is a of in the family from the Mediterranean Sea. Whether A. sulcata should be recognized as a synonym of remains a matter of dispute.


Description
This sea anemone has two ; one has a basal disk up to in diameter and has fewer than 192 tentacles (usually 142 to 148); the other has a disk up to in diameter and 192 tentacles or more, up to 348. The tentacles are long, slender and tapering, arranged in six whorls round the central mouth on the oral disk. They vary in colour but are usually some shade of green, grey or light brown. A knob on the tip of each tentacle, where the stinging cells are concentrated, may be violet.


Distribution and habitat
This sea anemone is native to the Mediterranean Sea and the eastern as far south as . It is found in the and the , on rocky ledges, in crevices and on boulders. Ecotype 1 occurs down to about while ecotype 2 occurs down to about .


Biology
Anemonia sulcata has a relationship with , which inhabit the tissues and provide energy for the sea anemone. It is , with individuals becoming sexually mature when they weigh about and the basal disc measures about across. There are no , and the develop inside the and break through the to enter the and thence move into the . At this stage, the already contain symbiotic zooxanthellae. Fertilisation takes place in the sea. Breeding seems to take place throughout the year, but peaks between March and May. The sea anemones can also reproduce asexually.

This sea anemone aggressively defends its territory from other individuals which are genetically dissimilar. It extends specialised tentacles (called acrorhagi), the tips of which have a concentration of (stinging cells); these sting the invader, causing tissue , and making the competitor move away.

(2025). 9789401132404, Springer Science & Business Media. .


Uses
This sea anemone is popular as a in southern Spain, specially, Cádiz, where it is known as or ; for the fishery to be sustainable, the authorities have set a minimum weight below which the sea anemones cannot be harvested. To neutralize the poison, the anemones are marinated in water with vinegar. The usual recipe is to batter them in flour and maybe egg and fry them in olive oil until they develop a crunchy cover. Ortiguilla omelets are also cooked.


Toxicity
Anemonia sulcata have toxic cnidocysts organelles that are able to inject venom and cause an allergic reaction, particularly a skin reaction. Their stings are known to cause and act on the sodium and potassium channels but also cause cytolysis on the cell membranes.Tezcan, O. D., and O. Gozer. 2015. Severe Toxic Skin Reaction Caused by a Common Anemone and Identification of the Culprit Organism. Journal of Travel Medicine 22:269–271.

A research conducted in rabbits' ventricular myocytes were analyzed under exposure to these toxins to better understand their role. Specifically, toxin ll (ATX ll) derived from the Anemonia sulcata was used in rabbit's myocytes to determine whether they induced the late sodium current causing overloading of sodium ions and consequently calcium ions inside the cell via reverse Na+/Ca2+ exchanger current. Since the heart depends heavily on the balance of Na+ and Ca2+ homeostasis, any unbalance from this can result in heart arrhythmias. These toxins induce augmentations in diastolic Ca2+ concentration, calcium transient amplitude, and myocyte shortening therefore increasing serious cardiac failure and cell apoptosis.Cao, Z., Z. Liu, P. Zhang, L. Hu, J. Hao, P. Zhang, Y. Tian, Z. Song, Q. Zhou, and J.-hua Ma. 2018. Sodium Houttuyfonate Inhibits Voltage-Gated Peak Sodium Current and Anemonia Sulcata Toxin II-Increased Late Sodium Current in Rabbit Ventricular Myocytes. Pharmacology 102:253–261.

In addition, the toxin AsKC11 is found in the venom of Anemonia sulcata. This toxin has been shown to be an activator of G protein-coupled inwardly-rectifying potassium (GIRK) channels 1/2, involved in the regulation of cellular excitability.

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